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. 2017 Aug 11;7(13):3369–3386. doi: 10.7150/thno.20678

Figure 6.

Figure 6

Oriented Fluorescence Imaging and Histopathology. Representative mouse in vivo FR images and corresponding oriented histopathology sections of metastatic cervical lymph nodes in mice administered AVB-620. Consecutive paraffin sections of each lymph node were processed for cytokeratin and/or H&E staining. (A) in vivo Cy5/Cy7 FR image of the 4T1 metastatic lymph node. (B) cytokeratin stained and (C) H&E stained. Images D & E are representative data from PyMT model. (D) AVB-620 in vivo Cy5/Cy7 FR image and (E) H&E stained lymph node. Ratio images used an RGB scale where red is high ratio and blue is low ratio. The dotted oval outlines the region of cancer invasion.