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. 2017 Sep 8;16:1536012117729044. doi: 10.1177/1536012117729044

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — Dual-model microCT/FMT imaging on intestinal adenomas in Apc ^Min/+ mice. A, Tumor nodules were detected by contrast-enhanced microCT imaging (white arrows). B, Coregistration of microCT image with 3-dimensional (3D) fluorescence image activated by ProSense 680 probe. Three-dimensional image was taken at 24 hours after injection of ProSense 680 activatable probe and fused with microCT image for anatomical colocalization. C, Two-dimensional fluorescence reflectance imaging (FRI) images of small intestine. After coregistration of in vivo imaging, the small intestine was dissected and imaged ex vivo by FRI for validation.