Table 2. Reclassification of individuals with discordant T2D status based on prevailing diagnostic thresholds for FG and HbA1c before and after accounting for the effect of erythrocytic variants.
FG ≥ 7 mmol/L but HbA1c < 6.5% (N = 390) | FG < 7mmol/L but HbA1c ≥ 6.5% (N = 266) | |||
---|---|---|---|---|
Not reclassified after accounting for the effect of erythrocytic variants | Reclassified to HbA1c ≥ 6.5% after accounting for the effect of erythrocytic variants | Not reclassified after accounting for the effect of erythrocytic variants | Reclassified to HbA1c < 6.5% after accounting for the effect of erythrocytic variants | |
European | 314 | 1 (0.3%) | 67 | 13 (16.3%) |
African | 64 | 4 (6.3%) | 81 | 28 (25.7%) |
Asian | 7 | 0 (0.0%) | 68 | 9 (11.7%) |
Total | 385 | 5 (1.3%) | 216 | 50 (18.8%) |
FG, fasting glucose; HbA1c, glycated hemoglobin