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. 2017 Apr 28;7(5):564–570. doi: 10.1016/j.apsb.2017.04.001

Table 1.

The resistance profile of KB/ATO cell.

Substrate	IC₅₀ value ± SD^a (μmol/L)		Resistance fold^b
Substrate	KB-3-1	KB/ATO	Resistance fold^b
ATO	2.07 ± 0.92	21.07 ± 2.47	10.04^*
APT	16.29 ± 7.19	220.36 ± 40.41	13.52^*
6-MP	7.86 ± 0.84	68.84 ± 2.88	8.75^*
Cisplatin	1.66 ± 1.46	8.43 ± 2.43	5.07^*
Vincristine	0.067 ± 0.036	0.20 ± 0.039	2.98^*
Paclitaxel	0.054 ± 0.019	0.080 ± 0.013	1.48
Doxorubicin	0.91 ± 1.14	1.56 ± 1.23	1.71
Mitoxantrone	0.25 ± 0.22	0.23 ± 0.18	0.92

^a

IC₅₀ values are represented as mean±SD of three independent experiments performed in triplicate.

^b

Resistance fold was calculated by dividing the IC₅₀ values of substrates by the IC₅₀ of parental cells.

^*

P < 0.05 versus parental cells.