Fig 4. Cell death profile after treatment with IC₅₀ of the ExEP-P and ExEP-A.

(A) Dot plots indicating the flow cytometry, and (B) representative diagrams obtained via flow cytometry of cells stained with annexin V-FITC/PI; Anx^–/PI^–: viable cells; Anx⁺/PI^–: apoptotic cells; Anx^–/PI⁺: necrotic cells, and Anx⁺/PI⁺: cells in late apoptosis. ***p < 0.001 treated group versus control viable cells. ^###p < 0.001 treated group versus control apoptosis. ⁺⁺⁺p < 0.001 treated group versus control necrosis. ^xxxp < 0.001 and ^xp < 0.05 treated group versus control late apoptosis.