Table 1. The adverse reaction of 11 kinds of treatments for IMN.
Treatments (N) | Infection | Bone marrow suppression | Abnormal liver function | Incidence of hypertension | Incidence of DM | Relapse |
---|---|---|---|---|---|---|
CTX (n = 448) | 68 | 10 | 18 | 2 | 19 | 4 |
Control (n = 497) | 6 | 0 | 0 | 1 | 2 | 8 |
Chlorambucil (n = 244) | 19 | 19 | 1 | 1 | 1 | 40 |
Tacrolimus (n = 177) | 38 | 0 | 10 | 8 | 30 | 2 |
CsA (n = 137) | 8 | 0 | 0 | 12 | 0 | 29 |
MMF (n = 71) | 14 | 6 | 2 | 1 | 1 | 2 |
Steroids (n = 309) | 5 | 0 | 0 | 6 | 1 | 32 |
Azathioprine (n = 34) | 2 | 5 | 1 | 3 | 0 | 5 |
Mizoribine (n = 62) | 0 | 0 | 0 | 0 | 0 | 0 |
ACTH (n = 15) | 0 | 0 | 0 | 0 | 0 | 0 |
LEF (n = 24) | 0 | 0 | 0 | 0 | 0 | 0 |
CTX: cyclophosphamide; CsA: cyclosporine; MMF: mycophenolate mofetil; LEF: leflunomide