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Schematic representation of the structure of the SERCA2a (10 transmembrane helices) and SERCA2b (11 transmembrane helices) calcium pumps. Slightly modified (by adding a horseshoe-shaped string (in yellow) representing the binding of (endo- or exogenous) sesquiterpenoids linking the TM loops 3, 5 and 7): after Dhitavit et al. in Br J Derm 2004, Vol 150, page 823.55 With permission from the publisher.
