A. Schematic illustration of a coronal mouse brain section showing the location of the cortical stroke cavity. The magnified schematics illustrate the no gel, the nano-porous and the MAP hydrogel injection conditions. B. Fluorescent images of GFAP staining showing post-stroke astrocytic response in the different conditions (scale 100 μm). C. Iba-1 staining showing post-stroke microglial response in the different conditions (scale 100 μm). D. Analysis of the GFAP positive response in terms of scar thickness, astrocytic infiltration in the infarct area and the positive area for GFAP signal in both infarct and peri-infarct regions. E. Analysis of the Iba-1 positive response in terms of positive area for GFAP signal in both infarct and peri-infarct regions. *, ** and **** indicate P < 0.05, P < 0.01 and P < 0.0001, respectively (Anova 1 way, Tukey's opst-hoc test).