Table 1.

The effects of GA treatment on cytokine levels in WT and CAG140 KI mice.

	HD Veh vs. WT Veh:		WT GA vs. WT Veh		HD GA vs. HD Veh:
Cytokine:	FC:	p-value:	FC:	p-value:	FC:	p-value:
IL1A	1.48	0.0007	1.78	0.180	0.81	0.048
IL1B	1.05	0.0284	1.38	0.213	0.84	0.073
IL2	1.32	0.0205	1.53	0.100	0.81	0.061
IL4	1.55	0.0074	1.48	0.103	0.76	0.036
IL6	1.81	0.0004	1.42	0.170	0.94	0.144
IL10	2.06	0.0004	1.36	0.149	0.87	0.111
IL12	1.76	0.0084	1.45	0.197	0.72	0.013
IL17A	1.70	0.0086	1.41	0.198	0.79	0.094
IFNg	0.92	0.2412	1.31	0.090	0.85	0.154
TNF-a	1.37	0.0178	1.37	0.155	0.88	0.224
G-CSF	1.37	0.0140	1.31	0.232	0.85	0.188
GM-CSF	1.52	0.0078	1.29	0.241	0.80	0.070

These data reflect cortical levels of the indicated cytokines after GA treatment (50 mg/kg; s.c. 5× week; 4 months duration). Significant differences are indicated in bold. P-values reflect significant differences as determined by Student’s t test (unpaired; two-tailed) from male mice only (n=4 mice per group).