Fig. 2.

Geraniin suppresses cell viability and induces apoptosis in glioma cells. a U87 and LN229 NSCLC cells and normal human astrocytes were treated with geraniin at 5–80 μM for 48 h and tested for cell viability by the MTT assay. b, c Flow cytometric analysis of apoptosis after Annexin-V/PI staining. b Representative dot plots of Annexin V-FITC/PI staining of U87 and LN229 50 cells treated with or without geraniin (80 μM). c Geraniin at 5–80 μM caused a concentration-dependent apoptosis in U87 and LN229 cells. d Measurement of caspase-3 activity in U87 and LN229 cells treated with indicated concentrations of geraniin. *P < 0.05 versus control