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. 2017 Aug 14;174(19):3302–3314. doi: 10.1111/bph.13948

Table 3.

Lungs and liver congestion indexes of control rats (CTR) and rats with heart failure (MCT) after 14 days of p.o. administration with PTS : HPβCD complex at 25, 50 or 100 mg·kg−1 dose

Groups Lungs wet weight/dry weight (g) Lungs wet weight/BW (mg·g−1) Liver wet weight/dry weight (g) Liver wet weight/BW (mg·g−1)
CTR0 2.4 ± 0.12 2.97 ± 0.35 2.85 ± 0.04 31.64 ± 2.43
CTR25 2.2 ± 0.13 2.69 ± 0.14 2.86 ± 0.04 31.86 ± 2.43
CTR50 2.43 ± 0.14 3.11 ± 0.41 2.84 ± 0.05 32.89 ± 2.80
CTR100 2.31 ± 0.12 2.31 ± 0.35 2.86 ± 0.04 32.87 ± 2.43
MCT0 2.7 ± 0.10a 4.31 ± 0.27a 2.95 ± 0.03 35.56 ± 1.43
MCT25 2.57 ± 0.10a 4.37 ± 0.26a 2.86 ± 0.03 34.37 ± 1.83
MCT50 2.36 ± 0.11a 3.85 ± 0.27a 2.85 ± 0.03 34.10 ± 1.85
MCT100 2.68 ± 0.10a 3.62 ± 0.29a 2.88 ± 0.04 36.56 ± 1.98

Values are expressed as mean ± SD, n = 8 animals per group. Two‐way ANOVA and Tukey's post hoc tests were performed. BW, body weight.

a

Significantly different compared with CTR group.