Figure 5.

The expression of 5‐HT_2A receptors in DRG neurons and colon, and colonic 5‐HT contents. Rats were administered sodium butyrate or saline via colonic instillation twice daily for 3 days (A–D). After the last administration, chlorpromazine (4 mg·kg⁻¹) or vehicle (saline) was administered p.o. Two hours later, the L5‐S1 DRG or colon was removed from the rats and tissues were subjected to Western blot analysis (A–C) or 5‐HT elisa assay (D). (A) and (B) show representative data of immunoblotting. (C) The relative data of band intensity at (A) and (B). Values are mean ± SEM; ^* P < 0.05 vs. saline.