Table 4.
Risk factors for CLI in diabetes by binary logistic regression analysis.
| OR | 95% CI for OR | P | OR* | 95% CI for OR* | P * | |
|---|---|---|---|---|---|---|
| Sex | 0.494 | 0.258–0.946 | 0.033 | ∕ | ∕ | ∕ |
| Age | 1.160 | 1.110–1.214 | 0.000 | ∕ | ∕ | ∕ |
| T2D Duration | 1.163 | 1.098–1.231 | 0.000 | ∕ | ∕ | ∕ |
| SBP | 1.041 | 1.023–1.061 | 0.000 | ∕ | ∕ | ∕ |
| TC | 0.652 | 0.466–0.913 | 0.013 | ∕ | ∕ | ∕ |
| Apo A | 0.061 | 0.011–0.333 | 0.001 | ∕ | ∕ | ∕ |
| Cr | 1.024 | 1.008–1.039 | 0.002 | ∕ | ∕ | ∕ |
| BUN | 1.319 | 1.103–1.577 | 0.002 | ∕ | ∕ | ∕ |
| Total bilirubin | 0.867 | 0.807–0.931 | 0.000 | ∕ | ∕ | ∕ |
| Trappin-2 | 1.065 | 1.035–1.095 | 0.000 | 0.987 | 0.933–1.043 | 0.637 |
| IGFBP-6 | 1.005 | 1.001–1.008 | 0.005 | 0.993 | 0.984–1.002 | 0.117 |
| BMP-4 | 1.001 | 1.000–1.003 | 0.039 | 1.001 | 0.997–1.004 | 0.709 |
| Decorin | 1.000 | 1.000–1.001 | 0.005 | 1.000 | 0.999–1.001 | 0.744 |
| Siglec-5 | 1.043 | 1.029–1.057 | 0.000 | 1.077 | 1.028–1.128 | 0.002 |
| TIMP-4 | 1.000 | 1.000–1.001 | 0.003 | 0.994 | 0.000–3066.573 | 0.999 |
| CDH5 | 1.106 | 1.050–1.166 | 0.000 | 1.205 | 1.003–1.449 | 0.057 |
CI, confidence interval. Logistic regression models were used to calculate OR. *Adjusted for sex, age, T2D Duration, SBP, TC, Apo A, Cr, BUN, Total bilirubin. pg/ml (Trappin-2, IGFBP-6, BMP-4), ng/ml (Decorin, Siglec-5, TIMP-4). All study subjects were included in the analysis. Significant values are marked in italic.