Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 12;7:11408. doi: 10.1038/s41598-017-11628-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

DXN inhibiting Aβ toxicity was at least partially mediated by DAF-16. (A) DXN inhibiting worm paralysis induced by Aβ over-expression was partially reverted by daf-16 RNAi. (B) The effect of DXN was similar partially reverted by daf-16 deletion. (C) Pdaf-16::gfp reporter was induced in worm strain TJ356 after treatment with 15 mg/mL DXN, and heat shock treatment at 37 °C for 15 min as a positive control. The scale bar was 80 μm. (D) Quantification of DAF-16 nuclear localization. In A and B, data are the average of three replicates with about 120-180 worms in each group. In C and D, animals were about 90 individuals. ***Indicated that there was significant difference between treatment group and control group at P < 0.001. There is significant difference among these groups when symbols are different (P < 0.05).