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. 2017 Sep 12;7:11301. doi: 10.1038/s41598-017-11310-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Some ALCL cases showed clonal TCR expression at the mRNA level. (A) Contribution of CDR3α and CDR3β sequences to the TCR repertoire in 10 normal T cell sets, 22 ALCL samples, and one ALCL cell line. (B) Expression of α, β, γ, and δ chains of TCR in primary cells, cell lines, and different subtypes of PTCL samples. (C) Expression of γ, δ, ε, and ζ chains of CD3 in primary cells, cell lines, and different subtypes of PTCL samples. Samples that do not express TCR transcripts (below the cut-off according to Figure 2) were excluded.