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. 2017 Sep 12;7:11279. doi: 10.1038/s41598-017-11802-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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fMRI results. Activations correlated with the sensation of low temperature in the dorsal margin of the left posterior insula extending to the putamen (a), the left and right retrosplenial cortices ((b and c) respectively), and the left amygdala (d) presented using a red–yellow scale on the standard anatomical image of SPM12. The statistical threshold was set to p < 0.005 at the voxel level and corrected for a family-wise error (FWE) rate of p < 0.05 for multiple comparisons.