Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 12;7:11402. doi: 10.1038/s41598-017-11035-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(a,b) IGV representation of the VHL locus of SKRC7 and SKRC7-VHL^HA cells. BAM files containing whole RNAseq data from these cell lines were loaded into IGV. Note the CAA-UAA mutation, resulting in the VHL ^Q132-stop mutation at the protein level. c and d show SeqNext representations of the same VHL locus of SKRC7 (c) and SKRC7-VHL^HA cells (d). (e) bar graph showing VHL-related TPM and FPM values of SKRC7 and SKRC7-VHL^HA. (f) Western blot of SKRC7 cells and the VHL-expressing derivative, stained with an anti-HA antibody and an antibody against GAPDH as control house keeping protein. Panel f represents 2 cropped images from different western blots, loaded with the same protein samples, derived from SKRC7 and SKRC7-VHL cells as indicated. The corresponding full blots are presented in Supplementary Figure 2.