Table 1.
Metabolic transcripts for smMIP design.
| Gene Symbol | Gene name | RefSeq mRNA ID (hg19) |
|---|---|---|
| ABAT | (4-)Aminobutyrate transaminase | NM_001127448.1 |
| ACACA | Acetyl-CoA carboxylase alpha | NM_198834.2 |
| ACACB | Acetyl-CoA carboxylase beta | NM_001093.3 |
| ACLY | ATP citrate lyase | NM_001303275.1 |
| ACO2 | Acotinase 2 | NM_001098.2 |
| ACSS2 | Acetyl-CoA synthetase | NM_001242393.1 |
| ALDOA | Aldolase, fructose-bisphosphate A | NM_000034.3 |
| ARHGAP26 | Rho GTPase activating protein 26 | NM_015071.4 |
| ATG4A | Autophagy related 4 A, cysteine peptidase | NM_052936.3 |
| ATP5A1 | ATP synthase complex, F1-ATP SYNTHASE SUBUNIT | NM_001257335.1 |
| ATP5C1 | ATP synthase complex, F1-ATP SYNTHASE SUBUNIT | NM_001001973.1 |
| BCAT1 | Branched chain amino-acid transaminase 1, cytosolic | NM_001178094.1 |
| BCAT2 | Branched chain amino-acid transaminase 2, mitochondrial | NM_001284325.1 |
| C12orf5 (TIGAR) | TP53-induced glycolysis regulatory phosphatase | NM_020375.2 |
| CA12 | Carbonic anhydrase XII | NM_206925.2 |
| CA9 | Carbonic anhydrase IX | NM_001216.2 |
| CBR1 | Carbonyl reductase 1 | NM_001286789.1 |
| CBS | Cystathione β-synthase | NM_000071.2 |
| CHKA | Choline kinase alpha | NM_212469.1 |
| CKB | Creatine kinase, braintype | NM_001823.4 |
| CPT1A | Carnitine palmitoyltransferase | NM_001031847.2 |
| CS | Citrate synthase | NM_004077.2 |
| CYCS | Cytochrome C, somatic | NM_018947.5 |
| D2HGDH | D-2-hydroxyglutarate dehydrogenase | NM_152783.4 |
| EGLN1 | Prolylhydroxylase | NM_022051.2 |
| ENO1 | Enolase 1, (alpha) | NM_001428.3 |
| EPAS1 | Hypoxia-inducible factor 2-alpha | NM_001430.4 |
| FASN | Fatty acid synthase | NM_004104.4 |
| FH | Fumarate hydratase | NM_000143.3 |
| G6PC | Glucose-6-phosphatase, catalytic subunit | NM_000151.3 |
| G6PD | Glucose-6-phosphate dehydrogenase | NM_000402.4 |
| GAD1 | Glutamate decarboxylase | NM_000817.2 |
| GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | NM_002046.5 |
| GCLC | Glutamate cysteine ligase | NM_001498.3 |
| GCLM | Glutamate cysteine ligase | NM_001308253.1 |
| GFPT1 | Fructose-6-phosphate amido-transferase | NM_001244710.1 |
| GLDC | Glycine dehydrogenase | NM_000170.2 |
| GLS | Glutaminase | NM_001256310.1 |
| GLUD1 | Glutamate dehydrogenase 1 | NM_005271.3 |
| GLUD2 | Glutamate dehydrogenase 2 | NM_012084.3 |
| GLUL | Glutamine synthetase | NM_001033056.3 |
| GOT1 | Glutamate oxaloacetate transaminase | NM_002079.2 |
| GPI | Glucose-6-phosphate isomerase | NM_001289789.1 |
| GPI | Phosphoglucose isomerase = GPI | NM_001289790.1 |
| GPT | Glutamate pyruvate transaminase | NM_005309.2 |
| GSS | Glutathione synthetase | NM_000178.2 |
| HIF1A | Hypoxia-inducible factor 1-alpha | NM_001530.3 |
| HK1 | Hexokinase 1 | NM_000188.2 |
| HK2 | Hexokinase 2 | NM_000189.4 |
| HK3 | Hexokinase 3 | NM_002115.2 |
| IDH1 | Isocitrate dehydrogenase 1 (NADP + ), soluble | NM_005896.3 |
| IDH2 | Isocitrate dehydrogenase 2 (NADP + ), mitochondrial | NM_002168.3 |
| IDH3A | Isocitrate dehydrogenase 3, mitochondrial, alpha | NM_005530.2 |
| IDH3B | Isocitrate dehydrogenase 3, mitochondrial, beta | NM_006899.3 |
| IDH3G | Isocitrate dehydrogenase 3, mitochondrial, gamma | NM_174869.2 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase | NM_024884.2 |
| LDHA | Lactate dehydrogenase A | NM_001135239.1 |
| LDHB | Lactate dehydrogenase B | NM_001174097.2 |
| MAPK8 | Mitogen-activated protein kinase 8 | NM_001278547.1 |
| MDH1 | Malate dehydrogenase 1 | NM_001199111.1 |
| MDH2 | Malate dehydrogenase 2 | NM_001282403.1 |
| MYC | V-myc avian myelocytomatosis viral oncogene homolog | NM_002467.4 |
| NAMPT | Nicotinamide phosphoribosyltransferase | NM_005746.2 |
| NAPRT1 | Nicotinate phosphoribosyltransferase | NM_145201.5 |
| NOX1 | NADPH oxidase 1 | NM_007052.4 |
| NOX3 | NADPH oxidase 3 | NM_015718.2 |
| NOX4 | NADPH oxidase 4 | NM_016931.4 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | NM_000903.2 |
| OGDH | Oxoglutarate (alpha-ketoglutarate) dehydrogenase | NM_001003941.2 |
| PARP1 | Poly (ADP-ribose) polymerase 1 | NM_001618.3 |
| PC | Pyruvate carboxylase | NM_000920.3 |
| PDHA1 | Pyruvate dehydrogenasealpha 1 | NM_000284.3 |
| PDK1 | Pyruvate dehydrogenase kinase 1 | NM_001278549.1 |
| PFKFB1 | Phosphofructokinase 2, PFKFB1 | NM_001271805.1 |
| PFKM | Phosphofructokinase 1, PFKM | NM_001166686.1 |
| PGAM1 | Phosphoglycerate mutase 1 | NM_002629.3 |
| PGD | Phosphogluconate dehydrogenase | NM_002631.3 |
| PGK1 | Phosphoglycerate kinase 1 | NM_000291.3 |
| PGK2 | Phosphoglycerate kinase 2 | NM_138733.4 |
| PKM | Pyruvate kinase, muscle | NM_001206796.2 |
| PRDX1 | Peroxiredoxin 1 | NM_001202431.1 |
| PRKAA1 | AMP-activated protein kinase, AMPK, catalytic subunit α1 | NM_006251.5 |
| PRKAA2 | AMP-activated protein kinase, AMPK, catalytic subunit α2 | NM_006252.3 |
| RPIA | Ribose 5-phosphate isomerase A | NM_144563.2 |
| SDHA | Succinate dehydrogenase complex, subunit A | NM_001294332.1 |
| SDHB | Succinate dehydrogenase complex subunit B | NM_003000.2 |
| SDHC | Succinate dehydrogenase complex, subunit C | NM_003001.3 |
| SDHD | Succinate dehydrogenase complex, subunit D | NM_003002.3 |
| SLC16A1 | Monocarboxylate transporter 1 | NM_001166496.1 |
| SLC16A3 | Monocarboxylate transporter 4 | NM_001206952.1 |
| SLC16A7 | Monocarboxylate transporter 2 | NM_001270622.1 |
| SLC1A2 | Glutamate transporter, high glial high affinity 2 | NM_001195728.2 |
| SLC25A5 | Adenine nucleotide translocase 2 | NM_001152.4 |
| SLC2A1 | Glucose transporter 1 | NM_006516.2 |
| SLC2A3 | Glucose transporter 3 | NM_006931.2 |
| SLC5A1 | Sodium glucose cotransporter | NM_001256314.1 |
| SLC7A1 | Cationic amino acid transporter, y + system | NM_003045.4 |
| SLC9A1 | Na+/H+ proton antiporter | NM_003047.4 |
| SOD1 | Superoxide dismutase 1 | NM_000454.4 |
| SOD2 | Superoxide dismutase 2, mitochondrial | NM_000636.2 |
| TALDO1 | Transaldolase | NM_006755.1 |
| TP53I3 | Tumor protein p53 inducible protein 3 | NM_004881.4 |
| TXN | Thioredoxin | NM_001244938.1 |
| VHL | Von Hippel Lindau | NM_198156.2 |