Table 2.

The 25 most highly expressed miRNAs in lung neutrophils from mice given PBS and the corresponding changes in expression during pneumonia.

Top 25 miRNAs expressed in PBS using LVS normalization (listed by expression value)	Fold change during pneumonia using LVS normalization	Top 25 miRNAs expressed in PBS using RMA normalization (listed by expression value)	Fold change during pneumonia using RMA normalization
mmu-miR-223-3p	2.1*	mmu-miR-223-3p	1.5
mmu-miR-21a-5p	1.3	mmu-miR-3963	−1.3*
mmu-miR-142-3p	1.7	mmu-miR-21a-5p	1.3*
mmu-let-7f-5p	−3.4*	mmu-miR-126-3p	−3.9*
mmu-let-7a-5p	−2.4*	mmu-miR-142-3p	1.6
mmu-miR-3963	−1.2	mmu-let-7f-5p	−2.4*
mmu-miR-126-3p	−4.2*	mmu-let-7a-5p	−1.8*
mmu-let-7c-5p	−2.6*	mmu-let-7c-5p	−2.6*
mmu-miR-26a-5p	−2.6*	mmu-miR-23a-3p	−1.5*
mmu-let-7b-5p	−3.2*	mmu-miR-26a-5p	−2.0*
mmu-miR-15a-5p	1.8*	mmu-let-7b-5p	−2.3*
mmu-miR-23a-3p	−2.1*	mmu-miR-29a-3p	1.2
mmu-miR-15b-5p	2.4*	mmu-miR-5100c	1.1
mmu-let-7g-5p	−1.1	mmu-miR-15b-5p	3.2*
mmu-miR-34b-5p	−8.0*	mmu-let-7g-5p	1.3*
mmu-miR-24-3p	−1.8*	mmu-miR-34b-5p	−6.7*
mmu-miR-29a-3p	−1.0	mmu-miR-16-5p	2.0*
mmu-miR-23b-3p	−2.8*	mmu-miR-15a-5p	2.3*
mmu-let-7i-5p	−1.6*	mmu-miR-24-3p	−1.5*
mmu-miR-19b-3pa	1.1	mmu-miR-26b-5p	1.1
mmu-miR-26b-5p	−1.1	mmu-let-7i-5p	−1.1
mmu-miR-16-5p	1.5*	mmu-miR-30a-5pd	−4.1*
mmu-miR-29c-3p	−1.1	mmu-let-7d-5p	−2.1*
mmu-let-7d-5p	−3.0*	mmu-miR-29c-3p	1.1
mmu-miR-107-3pb	−1.3	mmu-miR-29b-3p	−1.2

Data were normalized using LVS or RMA. Positive (negative) values indicate up (down) regulation of expression compared with PBS. *p ≤ 0.05 compared with PBS (FDR corrected). Notes on individual miRs; ^ammu-miR-19b-3p is ranked 30^th in RMA; ^bmmu-miR-107-3p is ranked 41^st in RMA; ^cmmu-miR-5100 was ranked 31^st in LVS; ^dmmu-miR-30a-5p is 42^nd in LVS.