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. 2017 Sep 12;7:11344. doi: 10.1038/s41598-017-10297-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ferritin Scaffolding mimics the positioning of Microtubule Organizing Centres of cells. (a) Representative observations of microtubule aster organization triggered by FKBP-TPX2, TPX2-ferritin, TXP2 ferritin-clusters, and centrosomes. Microtubules and ferritins are labelled with fluorescein-labelled tubulin and mCherry, respectively. (b) Geometrical positioning of asters nucleated by FKBP-TPX2, TPX2-ferritin, TXP2 ferritin-clusters, and centrosomes. 0 and ±1 indicate the centre and the droplet boundary, respectively. (c) Mean and standard deviation of the off-centring of the aster positions triggered by FKBP-TPX2, TPX2-ferritin, TXP2 ferritin-clusters, and centrosomes.