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. 2017 Sep 12;7:11427. doi: 10.1038/s41598-017-11331-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Concept lattice constructed from the comparison between breast cancers with highly suspicious calcifications and those without suspicious calcifications (n = 1838) in a total population with 60 clusters annotated by GO terms in the biological process category. Only 24 of 60 clusters demonstrate at least one significant GO term(s) (p < 0.001). Overall, the dataset shows 125 significant annotations with 106 unique GO terms. The core–periphery substructures are marked with colors (i.e., core in red, communicating in green, independent in yellow and peripheral in gray).