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. 2017 Sep 12;7:11403. doi: 10.1038/s41598-017-11500-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The results of antibody-mediated CDC to MCF-7 (A) and SKMEL-28 (B) cells, presented as cell lysis rates caused by treatment with rabbit complements and normal mouse serum, irrelevant 2H3 monoclonal antibody as negative control, or pooled antisera of GM2-MPLA conjugate 2 and GM2-KLH conjugate 3, respectively. The error bar shows the standard deviation of six parallel experiments. *The difference between the results of normal sera and the antisera of GM2-KLH and GM2-MPLA conjugates is statistically significant (P < 0.05).