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. 2017 Sep 12;7:11411. doi: 10.1038/s41598-017-11317-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlations between cortical gray matter volume and visual field loss in the Retinitis Pigmentosa patients. The same altered regions (Fig. 1) present a correlation between cortical gray matter volume and visual field extent in the Retinitis Pigmentosa patients (p < 0.001 with a cluster correction of 150 voxels). In the upper part, it is represented the direct (positive) correlation between gray matter volume and visual field diameter (in degrees). A smaller visual field diameter corresponds to reduced gray matter volume. In the lower part, it is displayed the inverse (negative) correlation between mean deficit (in dB) and gray matter volume. High mean deficit values correspond to reduced gray matter volumes. The color bar indicates the range of t-values with white/yellow representing more significant differences (higher t-values), orange indicating less significant differences (middle range t-values), and red indicating nonsignificant differences (lower t-values). (a) Sagittal view; (b) Coronal view; (c) Axial view. The cursor is positioned in the Montreal Neurological Institute coordinates with the maximum t-value [upper part −6, −76, 2 mm; lower part −8, −78, 4 mm (red arrow)].