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. 2017 Sep 12;7:11392. doi: 10.1038/s41598-017-11892-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of PAβN on QS signal molecules production. (A) 3OC₁₂-HSL (white bars), C₄-HSL (light-grey bars) and HHQ/PQS (dark-grey bars) production in P. aeruginosa PAO1 stationary phase cultures grown in LB or in LB supplemented with PAßN at the concentrations indicated below the histogram. (B) 3OC₁₂-HSL production in the indicated strains grown in LB (white bars), or in LB supplemented with 27 µM with PAßN (light-grey bars), with 1 mM MgSO₄ (dark-grey bars), or with 27 µM PAßN plus 1 mM MgSO₄ (black bars). The average of at least three independent experiments is reported with SD; statistical significance with respect to the untreated sample is indicated with one asterisk (p < 0.05).