Skip to main content
. 2017 Jul 22;36(10):2225–2236. doi: 10.1007/s10067-017-3745-z

Table 4.

Serological and histological features of pSS in paediatric studies

References Abnormal sialometry N (%) Abnormal salivary scintigraphy N (%) Abnormal ocular stain N (%) Positive biopsy N (%) Positive sialography N (%) Anti-SSA N (%) Anti-SSB N (%) Anti-SSA and/or anti-SSB N (%) Anti-ENA N (%) ANA N (%) RF N (%) Raised ESR N (%) Raised IgG N (%)
Yokogowa et al. [23] 5/7 (71.4)a 3/3 (100) 4/16 (25.0) 10/15 (66.7)b 15/15 (100)c 22/26 (84.6) 17/26 (65.4) 22 (84.6) 25 (96.2) 16 (72.7)
Cimaz et al. [24] 30 (75.0) 40 (100)d 40 (100) 29 (72.5) 34 (85.0) 30 (75.0) 27 (67.5) 21 (52.5)
Drosos et al. [22] 7 (53.8) 4 (30.8) 11 (84.6) 11 (84.6) 9 (69.2) 6 (46.2)
Stiller et al. [25] 9 (81.8)e 8 (72.7) 10 (90.9)d 10 (90.9) 4 (36.4) 3 (27.3) 7 (63.6) 7 (63.6) 3 (27.3) 2 (18.2)
Tomita et al. [26] 11 (26.2) 29 (69.0)f 31 (73.8)g 26 (61.9) 13 (31.0) 34 (81.0) 24 (57.1) 32 (76.2)

Anti-ENA- Anti-Extractable Nuclear Antigen; ANA- Anti-nuclear Antibody; ESR- Erythrocyte Sedimentation Rate; LSG FS- Labial Salivary Gland Focal Score; RF- Rheumatoid Factor

a<0.1 ml/min

bLSG FS >1

cLSG FS > 0

dCriteria unknown

e<0.02 ml/min

fGrade III/IV Greenspan Criteria

gStage III/IV Rubin and Holt Criteria