Table 1.
Linear mixed effect models for the relationship between viral loads, CD4 counts, CXCL13, and BAFF over time and B cell subsets in absence of early antiretroviral treatment.
| HIV-1 infected untreated |
||||||
|---|---|---|---|---|---|---|
| B cell subset | Activated memory | Resting memory | Tissue-like memory | Naive | Plasmablasts | |
| Viral Loads | Coef (SE) | 0.0604 (0.037) | −2.5253 (0.5238) | 0.1083 (0.0388) | −0.3031 (1.2403) | 0.1384 (0.0973) |
| p-Value | 0.103 | <0.0001 | 0.005 | 0.807 | 0.155 | |
| CD4 counts | Coef (SE) | −0.0006 (0.0002) | 0.0119 (0.0035) | −0.0005 (0.0002) | 0.0028 (0.0074) | −0.0010 (0.0005) |
| p-Value | 0.009 | 0.001 | 0.039 | 0.705 | 0.078 | |
| CXCL13 | Coef (SE) | 0.0008 (0.0006) | −0.0160 (0.0106) | 0.0007 (0.0007) | 0.0026 (0.0188) | 0.0010 (0.0013) |
| p-Value | 0.207 | 0.13 | 0.309 | 0.889 | 0.424 | |
| BAFF | Coef (SE) | 0.0003 (0.0001) | −0.0015 (0.0025) | 0.00002 (0.0001) | 0.0038 (0.0040) | 0.0007 (0.0003) |
| p-Value | 0.006 | 0.553 | 0.909 | 0.373 | 0.026 | |
Significant p values are shown in bold.