Figure 2.

Augmented IL-17 expression in mesenteric lymph nodes after Salmonella enterocolitis onset. Wild type and Jα18^−/− KO BALB/c mice pretreated with 20 mg of streptomycin received 3–4 × 10³ CFU of Salmonella enterica intragastrically. Five days after infection cytokine expression was analyzed by qPCR. Infected wild type mice (EC group); infected KO mice (KO EC group); infected wild type mice treated with anti-CD1d mAb (anti-CD1d EC group); uninfected wild type mice (Control group); uninfected KO mice (KO group); uninfected wild type animals treated with anti-CD1d mAb (anti-CD1d group). Expression levels for mRNA were determined and are presented in relation to 18S rRNA. ^*Significant differences between KO EC or anti-CD1d EC mice vs. EC group (p < 0.01). Results are expressed as mean ± SD (n = 4). Representative data from three independent experiments.