Table 4.

Biophysical properties of RS neurons at different recovery times following rostral (10% BL) or caudal (50% BL) spinal cord HTs

	N	Vrest, mV	Rin, MΩ	Vth, mV	VAP, mV	VfAHP, mV	VADP, mV	VsAHP, mV
Control (uninjured, 2 wk)	34	−75.7 ± 4.5	7.84 ± 3.36	16.4 ± 6.6	103.3 ± 7.0	−4.24 ± 3.95	2.02 ± 1.58	−1.57 ± 1.31
10% BL HT
2 wk	57	−74.2 ± 5.2	7.39 ± 3.72	24.9 ± 8.2**	105.9 ± 9.6	−11.92 ± 4.63***	0.03 ± 0.16***	−0.27 ± 1.13***
4 wk	21	−74.6 ± 5.2	8.35 ± 3.51	28.3 ± 10.6**	106.0 ± 12.3	−9.36 ± 4.74**	0.03 ± 0.13***	−0.21 ± 0.54***
6 wk	35	−73.4 ± 4.9	8.26 ± 4.21	24.6 ± 9.4**	105.3 ± 8.9	−9.85 ± 4.80***	0.35 ± 1.12***	−0.28 ± 0.61***
50% BL HT
2 wk	32	−76.4 ± 5.0	6.84 ± 2.75	19.7 ± 5.5	100.8 ± 11.7	−3.89 ± 4.27	2.43 ± 2.41	−1.38 ± 1.07
4 wk	20	−73.6 ± 3.4	6.83 ± 3.47	18.1 ± 5.1	102.0 ± 9.9	−3.39 ± 2.97	1.81 ± 1.95	−1.08 ± 1.19
6 wk	37	−76.2 ± 4.9	8.56 ± 3.22	18.1 ± 5.7	103.5 ± 7.0	−3.06 ± 2.31	2.20 ± 1.53	−1.80 ± 1.14

Values are means ± SD; N is no. of neurons (each group includes uninjured or injured RS neurons, regardless of side of brain). Control values are pooled data for uninjured RS neurons (mostly left side of brain) at 2-wk recovery times following right spinal HTs at 10% or 50% BL. Remaining values are for injured RS neurons (mostly right side of brain) following right spinal HTs at 10% or 50% BL. Statistics (ANOVA with Dunnett multiple comparisons posttest or Kruskal-Wallis with Dunn’s multiple comparisons posttest):

^**P < 0.01; ***P < 0.001 compared with properties of uninjured neurons in control group.