Table 2.
Histology, treatment, and SRS characteristics for all lesions biopsied by result
| Characteristic | Radiation Necrosis | Disease Recurrence | Exact P-value | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Diagnosis Type | |||||
| All other mets | 18 | 75.0 | 6 | 25.0 | 0.263 |
| Lung mets | 6 | 54.5 | 5 | 45.5 | |
| Age at SRS, y | |||||
| ≤53 | 14 | 73.7 | 5 | 26.3 | 0.364 |
| >53 | 10 | 62.5 | 6 | 37.5 | |
| Resection Pre-SRS | |||||
| No | 20 | 71.4 | 8 | 28.6 | 0.652 |
| Yes | 4 | 57.1 | 3 | 42.9 | |
| WBRT Pre-SRS | |||||
| No | 14 | 82.4 | 3 | 17.6 | 0.146 |
| Yes | 10 | 55.6 | 8 | 44.4 | |
| WBRT Post-SRS | |||||
| No | 20 | 69.0 | 9 | 31.0 | 0.999 |
| Yes | 4 | 66.7 | 2 | 33.3 | |
| Time from SRS to biopsy (mo) | |||||
| ≤9 mo | 9 | 47.4 | 10 | 52.6 | 0.004 |
| >9 mo | 15 | 93.8 | 1 | 6.3 | |
| Max Dose (Gy) | |||||
| ≤21 | 11 | 61.1 | 7 | 38.9 | 0.471 |
| >21 | 13 | 76.5 | 4 | 23.5 | |
| PTV (cm 3) | |||||
| ≤4 | 15 | 78.9 | 4 | 21.1 | 0.273 |
| >4 | 9 | 56.3 | 7 | 43.8 | |
| V12 (cm 3) | |||||
| ≤16 | 13 | 68.4 | 6 | 31.6 | 0.999 |
| >16 | 11 | 68.8 | 5 | 31.3 | |
| All Lesions | 24 | 68.6 | 11 | 31.4 | |