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Grades 3 and 4 treatment-related toxicities and time to engraftment
| TMZ Toxicities | Grade 3 | Grade 4 |
|---|---|---|
| Thrombocytopenia | 3 | 2 |
| Neutropenia | 1 | |
| Lymphopenia | 2 | 1 |
| Hyponatremia | 1 | 0 |
| ASCT Toxicities | Grade 3 | Grade 4 |
| Febrile neutropenia | 5 | 0 |
| ALT/AST | 3 | 0 |
| Infection | 0 | 1 |
| Diarrhea | 1 | 0 |
| Colitis | 0 | 1 |
| Mucositis | 1 | 0 |
| Rash | 1 | 0 |
| Syncope | 1 | 0 |
| Vasovagal malaise | 1 | 0 |
|
Time to engraftment:
Neutrophils (>500): 9 days (range: 8–12) Platelets (>50,000): 12 days (range: 9–18) | ||
Note: No toxic deaths observed.
