Table 2. Descriptive characteristics of the birth cohort of patients diagnosed with IBD with at least 1 year of continuous exposure to the rural/urban environment.
|
Alberta |
Manitoba |
Ontario |
Overall |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rural (n=65) | Urban (n=233) | P value | Rural (n=47) | Urban (n=149) | P value | Rural (n=219) | Urban (n=1,920) | P value | Rural (n=331) | Urban (n=2,302) | P value | |
| Age at diagnosis, mean±s.d. | 7.1±4.6 | 6.7±4.3 | 0.56 | 13.4±4.0 | 13.2±3.8 | 0.07 | 12.2±4.4 | 11.6±4.2 | 0.06 | 11.1±4.3 | 10.8±4.1 | 0.12 |
| Age at diagnosis median (IQR) | 7 (3–11) | 7 (3–11) | 1.0 | 14 (11–16) | 13 (11–16) | 0.66 | 13 (10–15) | 12 (9–15) | 12.4 (8.7–16.2) | 11.5 (7.5–15.6) | <0.0001 | |
| Female, N (%) | 28 (43.1%) | 117 (50.2%) | 0.31 | 22 (46.8%) | 73 (49.0%) | 0.87 | 90 (41.1%) | 839 (43.7%) | 0.62 | 140 (42.3%) | 1,029 (44.7%) | 0.41 |
| Longitudinal follow-up time, mean±s.d. | 7.2±4.6 | 6.1±4.3 | 0.09 | 6.5±3.1 | 7.5±3.1 | 0.08 | 15.6±3.7 | 15.5±3.6 | 0.57 | 10.8±6.4 | 11.3±5.7 | 0.21 |
| Continuous period in rural/urban (%) | ||||||||||||
| 1 year | 65 (100%) | 233 (100%) | NA | 47 (100%) | 149 (100%) | NA | 219 (100%) | 1,920 (100%) | NA | 331 (100%) | 2,302 (100%) | NA |
| 2 year | 65 (100%) | 233 (100%) | 47 (100%) | 148 (99.3%) | 208 (95.0%) | 1,902 (99.0%) | 320 (96.7%) | 2,283 (99.2%) | ||||
| 3 year | 65 (100%) | 229 (98.3%) | 40 (85.1%) | 146 (98.0%) | 200 (91.3%) | 1,851 (96.4%) | 305 (92.1%) | 2,226 (96.7%) | ||||
| 4 year | 62 (95.4%) | 227 (97.4%) | 36 (76.6%) | 146 (98.0%) | 185 (84.4%) | 1,806 (94.1%) | 283 (85.5%) | 2,179 (95.0%) | ||||
| 5 year | 60 (92.3%) | 218 (93.6%) | 36 (76.6%) | 145 (97.3%) | 172 (78.5%) | 1,746 (90.9%) | 268 (81.0%) | 2,109 (91.6%) | ||||
| Diagnosis, n (%) | ||||||||||||
| Crohn’s | 31 (47.7%) | 118 (50.6%) | 0.22 | 27 (57.5%) | 81 (54.4%) | 0.74 | 129 (58.9%) | 1,059 (55.2%) | 0.29 | 187 (56.5%) | 1,258 (54.6%) | 0.89 |
| Ulcerative colitis | 19 (29.2%) | 74 (31.8%) | 20 (42.5%) | 68 (45.6%) | 79 (36.1%) | 713 (37.1%) | 118 (35.6%) | 855 (37.1%) | ||||
| IBD type unclassifiable | 15 (23.1%) | 41 (17.6%) | NA | NA | 11 (5.0%) | 148 (7.7%) | 26 (7.9%) | 189 (8.2%) | ||||
| Diagnosis time period, n (%) | ||||||||||||
| 1994–2003a | 17 (28.3%) | 61 (27.6%) | 0.62 | 7 (14.9%) | 25 (17.0%) | 0.36 | 22 (10.0%) | 255 (13.3%) | 0.55 | 46 | 341 | NA |
| 2004–2008 | 43 (71.7%) | 160 (72.4%) | 15 (31.9%) | 61 (41.5%) | 109 (49.8%) | 948 (49.4%) | 167 | 1,169 | ||||
| 2009–2010 | NA | NA | 25 (53.2%) | 61 (41.5%) | 88 (40.2%) | 717 (37.3%) | 113 | 778 | ||||
a
Due to small cell sizes, descriptive characteristics of the birth cohort diagnosed 1994–2003 were combined in this table for Manitoba and Ontario. Alberta’s birth cohort included only patients diagnosed 1999–2003.