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. 2017 Sep 8;11:459. doi: 10.3389/fnins.2017.00459

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Copyright © 2017 Syed, Yang, Hu and Deshpande.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Step I: gRAICAR Analysis on Combined (Autism + Control) Group producing group level components x, y, and z. (B) Step II: gRAICAR Analysis on Autism Group Only, producing group-level components, x and x₁. x is discarded since it was produced in step I. (C) Step III: gRAICAR Analysis on Control Group Only, producing group-level components, y and y₁. y is discarded since it was produced in step I. (D) Step IV: Group level components from Steps II and III were combined by retrieving spatial maps corresponding to ICs these group-level components represented for each subject within each group as shown in the figure. Group level components reproducible in the combined group also found in individual analysis (steps II and III) were excluded.