Table 2.
Weighted multinomial logistic regression of factors associated with membership in Veterans Aging Cohort Study index score trajectories among HIV-positive participants.
| Characteristic | VACS index trajectory group, adjusted odds ratio (95% CI)
|
P value | |||
|---|---|---|---|---|---|
| Low | Moderate | High | Extreme | ||
| Age (per unit increase) | 0.94 (0.91–0.96) | REF | 1.12 (1.10–1.12) | 1.13 (1.12–1.15) | < 0.001 |
| Race (ref: White) | < 0.001 | ||||
| African American | 0.42 (0.26–0.66) | REF | 1.80 (1.52–2.14) | 2.58 (1.98–3.38) | |
| Other | 0.41 (0.16–1.05) | REF | 1.44 (1.01–2.04) | 2.41 (1.47–3.95) | |
| High school education | 1.30 (0.80–2.13) | REF | 0.77 (0.66–0.90) | 0.69 (0.56–0.84) | < 0.001 |
| Marital status (ref: Married) | 0.006 | ||||
| Divorced/separated/widowed | 1.35 (0.71–2.58) | REF | 1.03 (0.85–1.24) | 1.56 (1.18–2.07) | |
| Never married | 2.06 (1.16–3.64) | REF | 1.00 (0.82–1.21) | 1.28 (0.96–1.73) | |
| IDU, ever | 0.57 (0.31–1.08) | REF | 1.77 (1.52–2.07) | 2.03 (1.64–2.52) | < 0.001 |
| AUDIT-C group | REF | 0.002 | |||
| Abstainers | 1.92 (1.07–3.44) | REF | 1.18 (0.96–1.47) | 1.90 (1.40–2.57) | |
| Lower risk | 1.07 (0.64–1.79) | REF | 1.14 (0.95–1.36) | 1.35 (1.02–1.79) | |
| Moderate risk | REF | REF | REF | REF | |
| Higher risk | a | REF | 1.21 (0.89–1.63) | 1.83 (1.21–2.78) | |
Final model chosen using a manual backwards selection procedure based on the AIC, starting with all variables significant at P < 0.05 in Table 1. Inverse probability of censoring weights were used to account for loss to follow-up for reasons other than death. Final model also adjusted for year of recruitment. AIC, Akaike information criterion; AUDIT-C; alcohol use disorders identification test-consumption; CI, confidence interval; REF, reference; VACS, Veterans Aging Cohort Study.
a
Effect estimate could not be calculated because of zero cell counts.