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. 2017 Aug 25;7(8):e593. doi: 10.1038/bcj.2017.74

Table 2. Morphological analysis of blood cell types in the kidney marrow from SOX4 transgenic fish compared with wild type.

Total number of zebrafisha (n=65) Myeloid progenitors (blasts/blast-like; %) Myelomonocyte/neutrophil (%) Lymphocyte (%) Immature erythroid (%) Mature erythroid (%) M/E ratio
5M-wild-type (n=5) 5.27±0.74 45.00±5.36 15.33±1.36 10.27±1.82 24.13±3.19 5.08±1.57
9M-wild-type (n=5) 5.73±0.64 39.67±5.01 14.39±2.97 12.27±0.83 27.93±6.03 3.72:1±0.53
12M-wild-type (n=5) 7.00±1.10 42.07±3.18 16.20±1.12 10.06±2.55 24.67±4.16 4.61±0.64
15M-wild-type (n=6) 7.11±1.88 40.95±2.33 15.95±2.04 11.28±1.04 25.44±4.06 4.30±0.47
5M-SOX4 (n=12)# 7.64±2.56 37.53±5.22 13.33±1.65* 11.95±3.02 29.08±6.40 4.10±1.59
9M-SOX4 (n=12)# 14.86±7.07** 50.53±10.33* 9.69±1.65** 7.22±3.46* 17.78±5.19* 11.62±7.25**
12M-SOX4 (n=11)# 16.24±7.25** 58.33±7.14** 6.09±3.61** 6.21±2.16* 13.12±4.38** 13.55±5.45**
15M-SOX4 (n=9)# 14.19±5.16** 50.74±9.15* 9.59±1.38*** 7.15±3.29* 16.74±4.42** 10.48±4.08**

Abbreviations: M, month; M/E ratio, myeloid-to-immature erythroid ratio.

Significant differences between the SOX4 transgenic fish and wild-type are indicated (*P<0.05; **P<0.01; ***P<0.001) by Mann–Whitney U-test.

Significant difference of groups between the SOX4 transgenic fish and wild-type are indicated (#P<0.001) by one-way analysis of variance (ANOVA).

a

A total number of 300 cells per zebrafish was counted to classify the distribution and subtypes of these hematopoietic cells.