Table 1.
Author | Study type | Blinding | Treatment methods compared | PRP group vs. control group | No. of PRP injections | Outcome measures in study | Follow-up | Inclusion criteria | Exclusion criteria |
---|---|---|---|---|---|---|---|---|---|
Dragoo et al.12) | Randomised controlled trial | Double blinded | PRP injections vs. ultrasound guided dry needling (plus standardized eccentric exercises) | PRP (n=9), control (n=12) | 1 | Victorian Institute of Sports Assessment score Pain visual analogue scale Tegner activity scale Lysholm knee scale Short-form questionnaire |
3, 6, 9, and 12 weeks and >6 months | Patellar tendinosis with persistence of symptoms after 6 weeks (12 sessions) of physical therapy with eccentric exercise Confirmed by magnetic resonance imaging Aged >18 |
Previous injection or surgery in the affected knee Inability to complete patient reported outcome surveys |
Vatrano et al.13) | Randomised controlled trial | Single blinded | PRP injections vs. focused extracorporeal shock wave therapy (plus a standardized stretching and muscle strengthening protocol) | PRP (n=23), control (n=23) | 2 (1 per week for 2 weeks) | Victorian Institute of Sports Assessment score Pain visual analogue scale Modified Blazina scale |
2, 6, and 12 months | Chronic unilateral patellar tendinosis with symptoms >6 months and refractory to nonsurgical management “Washout period” of 12 weeks between any non-operative therapy and inclusion in the study Confirmed by ultrasound scan Athletic participants Aged 18–50 |
Bilateral complaints Signs or symptoms of other coexisting knee lesions; knee surgery or steroid injections within 3 months Signs of disorders Therapy with anticoagulants-antiaggregants; platelet values of fewer than 150,000/mm3 Pregnancy |
PRP: platelet-rich plasma.