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MiRs-143 and -145 enhance SMAD-dependent transcription. NMuMG cells either overexpressing (a) or sponged (b) for miR-143 or miR-145 were transiently transfected with a SMAD-luciferase reporter sensor, followed by 24 h treatment with TGF-β and assessment of luciferase activity upon Renilla normalization (mean±S.E.M. relative to untreated empty vector cells, n=3). P-values: *P<0.05; **P<0.01; ***P<0.001
