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. 2017 Aug 15;7(14):3478–3488. doi: 10.7150/thno.20717

Figure 2.

Figure 2

CBX8 plays paradoxical roles in ESCC, suppressing cell migration and invasion while promoting proliferation. (A) The expression of CBX8 in ESCC cell lines was detected at mRNA and protein levels by qRT-PCR and Western blotting (insertion panel), respectively. An immortalized esophageal epithelial cell line NE-1 was used as control. Data from three independent experiments are expressed as mean ± SD. ** p < 0.01 and *** p < 0.001, Student's t-test. (B, C) Both the cell migration and invasion assays were performed in the indicated stable cell lines as described in the Materials and methods. Representative images (100 ×) are shown. The columns, mean of three independent experiments; the bars, SD. ** p < 0.01 and *** p < 0.001 using Student's t-test. (D, E) The cell viability of the indicated stable cell lines was measured in different time points as indicated by MTT assay. Data from three independent experiments are expressed as mean ± SD. * p < 0.05 and ** p < 0.01, Student's t-test.