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. Author manuscript; available in PMC: 2017 Sep 13.
Published in final edited form as: Nat Prod Rep. 2011 May 9;28(7):1229–1260. doi: 10.1039/c0np00013b

Scheme 23.

Scheme 23

Enantioselective synthesis of sceptrin (146) by Baran.90 PLE = pig liver esterase, DMT-MM = 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, TsOH = p-toluenesulfonic acid, DIBAL = diisobutylaluminum hydride, MsCl = methanesulfonyl chloride, DMF = N, N-dimethylformamide, THF = tetrahydrofuran.