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. 2017 Aug 10;8(8):e2977. doi: 10.1038/cddis.2017.349

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The intensity of the Aβ oligomer is increased in certain region OB of Tg2576 mice compared with age-matched WT mice. (a and c) Evolution of the Aβ oligomer in WT versus Tg in 6-month-old (WT, n=7; Tg, n=7) (a) and 14-month-old (WT, n=9; Tg, n=8) (c). (b and d) Stereological analysis of the Aβ oligomer intensity (WT control in each group) in 6-month-old (b) and 14-month-old (d) mice. All data are presented as mean±S.E.M. Scale bar=10 μm. Two-way ANOVA, using Prism software (GraphPad software), *P<0.05 and ***P<0.001 denote statistical significance