Table 1. Thickness and cell numbers of the OE were decreased in Tg2576 mice compared with age-matched WT mice.
| (a) |
OE thickness, μm |
|||
|---|---|---|---|---|
|
6 months |
14 months |
|||
| WT | Tg | WT | Tg | |
| Ecto | 47.2±3.2 | 43.4±3.6 (**) | 48.6±8.3 | 42.8±4.6 (***) |
| Endo | 76.1±6.7 | 73.9±9.3 (*) | 77.1±8.1 | 70.2±3.2 (***) |
| (b) |
Total number of cells (2.5 mm2) |
|||
|---|---|---|---|---|
|
6 months |
14 months |
|||
| WT | Tg | WT | Tg | |
| Ecto | 42.7±5.6 | 38.0±5.7 (**) | 41.4±3.0 | 30.1±2.9 (***) |
| Endo | 83.1±7.0 | 79.0±8.8 (*) | 61.0±10.3 | 52.1±9.9 (***) |
(a) Thickness in each region of the OE in 6-month-old WT (n=7) versus Tg (n=7) and 14-month-old WT (n=9) versus Tg (n=8). Two-way ANOVA, using Prism software (GraphPad software), *P<0.05, **P<0.01, and ***P<0.001 denote statistical significance.
(b) The number of cells in each region of the OE in 6-month-old WT (n=7) versus Tg (n=7) and 14-month-old WT (n=9) versus Tg (n=8). Two-way ANOVA, using Prism software (GraphPad software), *P<0.05, **P<0.01, and ***P<0.001 denote statistical significance.