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. 2017 Aug 3;8(8):e2969. doi: 10.1038/cddis.2017.359

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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PEDF induces the change of EMT-related molecules in xenograft tissues. (a) The expression of E-cadherin, N-cadherin, slug, pERK1/2 and ERK1/2 was detected by western blotting in xenograft tissues. (b) IHC analysis of PEDF, LR, slug, N-cadherin and CD31 expression in intrahepatic metastasis tissues and lung metastasis tissues. Representative images are shown