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. 2017 Aug 10;8(8):e2981. doi: 10.1038/cddis.2017.385

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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YAP rescues the apoptosis-induced effect of DACT2 overexpressing on glioma cells. (a and b) Flow cytometric analysis was conducted to determine cellular apoptosis using annexin V/PI double staining. (c and d) Tunel assay of con cells, overDACT2 cells and overDACT2/overYAP cells observed by microscopy, scale bars: 100 μm (200 ×). con: transfected with empty vectors; overDACT2: transfected with DACT2 vectors, overDACT2/overYAP: transfected with DACT2 vectors and YAP vectors. (*P<0.05, **P<0.01, ***P<0.001, ^##P<0.01, ^###P<0.001)