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. 2017 Aug 10;8(8):e2981. doi: 10.1038/cddis.2017.385

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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DACT2 suppresses YAP signaling pathway though Wnt/β- catenin signaling pathway. (a and b) Western blotting analysis of the p-β-catenin, β-catenin, p-YAP and YAP expression in overDACT2 U251 and U87 cells. (c and d) Western blotting analysis of the p-YAP and YAP expression in sh-β-catenin U251 and U87 cells. (e and f) Western blotting analysis of the p-β-catenin, β-catenin, p-YAP and YAP expression in β-catenin-transfected U251 and U87 cells treated with DACT2. con: transfected with empty vectors; overDACT2: transfected with DACT2 vectors, overDACT2/over-β-catenin: transfected with DACT2 vectors and β-catenin vectors, shcon: transfected with control vectors, sh-β-catenin: transfected with sh-β-catenin vectors (*P<0.05, **P<0.01, ^#P<0.05, ^##P<0.01)