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. 2017 Aug 10;8(8):e2981. doi: 10.1038/cddis.2017.385

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The growth-suppressive effect of DACT2 overexpressing on glioma cells in vivo. (a) DACT2 inhibited the growth of U251 and U87 cells in vivo. (b and c) Tumor weight and growth curve. (d and e) IHC analysis of the protein expression of YAP, PCNA, CyclinD1 and Bax in transplanted tumors, scale bars: 50 μm (400 ×). con: transfected with empty vectors; overDACT2: transfected with DACT2 vectors (*P<0.05, **P<0.01, ***P<0.001)