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. 2017 Aug 10;8(8):e2989. doi: 10.1038/cddis.2017.391

Figure 6.

Figure 6

Effects of dioscin on ERβ signaling in PC3 cells were abrogated by ERβ- siRNA in vitro. (a) Effects of dioscin and ERβ-siRNA on cleaved caspase-3, cleaved PARP, Bax and Bcl-2 expression levels in PC3 cells. (b) Effects of dioscin and ERβ-siRNA on ERβ, PHD2, HIF-1α, VEGF-A and BMI-1 expression levels in PC3 cells. Data are presented as the mean±S.D. (n=5). **P<0.01 versus Control group; NS, not significant