Figure 1.

lncRNA XIST is significantly upregulated in CRC cell lines and tissues. (a) Relative expression level of lncRNA XIST in CRC cell lines (*P<0.05) (n=3 independent experiments). (b) Relative expression of lncRNA XIST expression in CRC tissues (n=115) and adjacent normal tissues (n=115) (*P<0.05) (n=3 independent experiments). (c) Relative expression level of lncRNA XIST in CRC tissues with (n=54) and without distant metastasis (n=61) (*P< 0.05) (n=3 independent experiments). (d) Relative expression level of lncRNA XIST in 70 male CRC tissues and the adjacent normal tissues (*P<0.05) (n=3 independent experiments). (e) Relative expression level of lncRNA XIST in 45 female CRC tissues and adjacent normal tissues (*P<0.05) (n=3 independent experiments). (f) Relative expression level of lncRNA XIST in different clinical stages (*P<0.05) (n=3 independent experiments). (g) Kaplan–Meier analysis of overall survival in CRC patients with high lncRNA XIST level (n=58) and low lncRNA XIST level (n=57) (P=0.01). Error bars represent the mean±S.D. values