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. 2017 Aug 24;8(8):e3011. doi: 10.1038/cddis.2017.421

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Knockdown of lncRNA XIST expression inhibits CRC cell growth, colony formation, migration and invasion in vitro. (a) Knockdown of lncRNA XIST inhibited cell proliferation as indicated by CCK-8 assays in HCT116 and SW620 cells (*P<0.05) (n=3 independent experiments). (b) Knockdown of lncRNA XIST inhibited colony formation as demonstrated by colony formation assays in HCT116 and SW620 cells (*P<0.05) (n=3 independent experiments). (c) Knockdown of lncRNA XIST inhibited cell migration in HCT116 and SW620 cells as indicated by wound healing assays (*P<0.05) (n=3 independent experiments). (d) Knockdown of lncRNA XIST inhibited cell invasion in HCT116 and SW620 cells as demonstrated by transwell assays (*P<0.05) (n=3 independent experiments). Error bars represent the mean±S.D. values