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. 2017 Sep 12;18:174. doi: 10.1186/s13059-017-1305-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Comparison of zeros in simulations based on the Tung dataset. The top row shows boxplots of the distribution of zeros per cell (a) and the difference from the real data (b). The distribution (c) and difference (d) in zeros per gene are shown in the middle row. The bottom row shows scatter plots of the relationship between the mean expression of a gene (including cells with zero counts) and the percentage of zeros as both the raw observations (e) and ranked differences from the real data (f)