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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):e60–e67. doi: 10.1097/MPG.0000000000001585

Table 2.

Association between breast milk cytokines and neonatal gut microbiome composition.

Adjustment Variable IL-10 TGFβ1 TGFβ2

PERMANOVAR2 (p-value)

(Unadjusted)* 0.017 (0.84) 0.024 (0.041) 0.026 (0.012)

Maternal EducationƗ 0.017 (0.86) 0.024 (0.040) 0.026 (0.014)

Household IncomeƗ 0.016 (0.97) 0.024 (0.041) 0.026 (0.009)

MarriedƗ 0.018 (0.65) 0.022 (0.11) 0.025 (0.023)

Urban ResidenceƗ 0.017 (0.85) 0.023 (0.10) 0.025 (0.026)

Maternal RaceƗ 0.018 (0.81) 0.021 (0.25) 0.024 (0.043)

Maternal AtopyƗ 0.017 (0.93) 0.024 (0.034) 0.026 (0.014)

Prenatal Antibiotic UseƗ 0.018 (0.78) 0.024 (0.079) 0.025 (0.040)

Prenatal Antifungal UseƗ 0.019 (0.76) 0.023 (0.13) 0.025 (0.043)

Season of BirthƗ 0.017 (0.90) 0.023 (0.071) 0.025 (0.021)

Mode of DeliveryƗ 0.018 (0.78) 0.024 (0.031) 0.026 (0.010)

GenderƗ 0.017 (0.84) 0.023 (0.057) 0.025 (0.018)

First Born ChildƗ 0.017 (0.91) 0.024 (0.044) 0.026 (0.014)

Prenatal Household Smoke ExposureƗ 0.017 (0.85) 0.023 (0.063) 0.025 (0.026)

Prenatal Indoor PetsƗ 0.018 (0.70) 0.025 (0.025) 0.026 (0.008)

Exclusive Breastfeeding at 1-Month InterviewƗ 0.018 (0.72) 0.022 (0.16) 0.024 (0.046)

Maternal Age at BirthƗ 0.018 (0.72) 0.023 (0.078) 0.025 (0.026)

Gestational AgeƗ 0.017 (0.86) 0.024 (0.051) 0.025 (0.017)

Birthweight Z-ScoreƗ 0.02 (0.61) 0.026 (0.035) 0.028 (0.014)

Days Postpartum at Milk Collection 0.018 (0.68) 0.024 (0.052) 0.025 (0.015)
*

Association between each breast milk cytokine and gut microbiome composition, unadjusted

Ɨ

Association between each breast milk cytokine and gut microbiome composition, adjusted for specified covariate

p<0.05 in bold