Table 3.
Highly significant KEGG pathways associated with the common 458 genes of chip A identified in FatiGO analysis
| Term | Name | P value | Genes |
|---|---|---|---|
| hsa05012 | Parkinson’s Disease Pathway | 3.82E-09 | SNCA,UBE2J1,NR4A2,NDUFA9,ATP5A1,UCHL1,VDAC3,NDUFA5,ATP5B,ATP5D,CYCS,ATP5O,CYC1,PINK1,NDUFAB1,ATP5G3 |
| hsa00190 | Oxidative phosphorylation | 3.50E-07 | NR4A2,NDUFA9,ATP5A1,ATP6V0D1,NDUFA5,ATP6V1B2,ATP5B,ATP6V0C,ATP6V1C1,ATP5D,ATP5O,CYC1,NDUFAB1,ATP5G3 |
| hsa05016 | Huntington disease | 3.64E-05 | NDUFA9,ATP5A1,VDAC3,NDUFA5,AP2M1,ATP5B,DCTN2,ATP5D,CYCS,ATP5O,CYC1,NDUFAB1,ATP5G3 |
| hsa05010 | Alzheimer’s disease | 9.90E-05 | SNCA,NDUFA9,ATP5A1,CALM3,NDUFA5,ATP5B,ATP5D,CYCS,ATP5O,CYC1,NDUFAB1,ATP5G3 |
| hsa04142 | Lysosomes | 1.63E-04 | SORT1,LAMP2,NPC1,IDS,AP3M2,NR4A2,AP3B2,ATP6V0D1,ATP6V0C,LAPTM4B |
| hsa03050 | Proteasome | 6.61E-04 | PSME3,PSMD12,PSMA1,PSMD8,PSMD1,PSMB2 |
| hsa04722 | Neurotrophin signaling pathway | 7.01E-04 | NFKBIA,SORT1,MAGED1,CALM3,NGFRAP1,YWHAZ,YWHAB,HRAS,ARHGDIA |